Virology Oncogenic viruses
Good afternoon, I'm interested in oncogenic viruses, namely the mechanisms of viral carcinogenesis
Hello what did I find
-viruses only initiate the pathological process, enhancing the processes of cell division and the genetic instability of the cells infected by them;
- in persons infected with oncogenic viruses, the occurrence of a tumor is usually an infrequent event: one case of a neoplasm occurs among hundreds, sometimes thousands of infected people;
- from the moment of infection to the onset of a tumor, there is a long latent period, lasting for years, sometimes decades;
- in most infected individuals, the occurrence of a tumor is not mandatory, but they may constitute a risk group, with a higher probability of its occurrence;
- For malignant transformation of infected cells, additional factors and conditions are required that lead to the progression of the most aggressive tumor clone.
The main mechanism of viral carcinogenesis is that the vibrio enters the cell and does not have a cytolytic effect, while the integration of proviral DNA into the cell genome occurs. As a result of this interaction, cell proliferation begins, which eventually becomes unlimited.
Thank you all for the explanation 😀