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Topic starter 12/02/2022 10:08 am
Hello, everyone! Could you tell me about the gene - CYP2D6. The gene encodes a special enzyme, which works in liver. What are the properties of the enzyme and how we can change its behavior?
12/02/2022 11:16 pm
This gene encodes the synthesis of cytochrome mooxygenases, which are involved in the oxidation of xenobiotics
morphism liked
14/02/2022 4:34 am
More than 80 allelic variants of the CYP2D6 gene are known, which are responsible for the pharmacodynamics and pharmacokinetics of drugs. CYP2D6 is one of the enzymes of the first phase of detoxification of the body and elimination of xenobiotics; it is involved in the metabolism of approximately 20% of drugs, including β-blockers (metoprolol, propranolol, timolol), antiarrhythmics, antihypertensive, psychotropic drugs, antidepressants and narcotic analgesics.
28/02/2022 11:41 pm
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