Pharmacology How to increase selectivity in drugs?
Hello, everyone! Does anybody know about the ways how to increase drugs' selectivity?
Hello! As far as I know, selectivity depends directly on their chemical structure, which determines the physicochemical properties and interaction with receptors.
@argentum could you imagine different isomers with different properties? Why is it so?
@morphism Yes, there are many such examples, with monosaccharides, amino acids. This is due to the fact that enzymes also have stereoisomers and react only with certain isomeric substrates due to their high specificity.
You are wellcome!