Pharmacology How to increase norepinephrine levels?

Posted by: @morphism

Hello, everyone! Do you know any specific biological mechanism, which can increase norepinephrine levels? Which make sense in terms of future drugs.

To increase the amount of the hormone in the body, it is necessary to eat foods that contribute to its increase. The synthesis of this neurotransmitter is a complex process:

The body synthesizes such an essential amino acid as phenylalanine;
An OH molecule is added to this amino acid to produce tyrosine, from which norepinephrine is produced.
Therefore, to increase the level of the hormone, you need to include in the daily diet foods high in protein.

Norepinephrine is generally a sympathetic neurotransmitter, so stimulation of the sympathetic nervous system leads to its release

@argentum you mean e.g. I should go for more stressful situations?)

@antony10 Could we start with food, which already has tyrosine? Like chicken.

@morphism Norepinephrine is produced in response to stress, fear, and similar emotions. Mobilizes the body in general in front of potential danger

@argentum Does it affect mood? Could it make you more focused?

@morphism I think yes 😉 

@morphism Rather excited, exciting

@argentum Interesting but some SNRI are used as focus enhancers...Like atomoxetine (Strattera) for ADHD

@antony10 I think so too, because we have atomoxetine...