Immunology What is an immune checkpoint inhibitor?
What is an immune checkpoint inhibitor?
It is a kind of medication (Nivolumab, Cemiplimab) that blocks certain proteins made by several cells of the immune system, T cells, and a type of cancer cell. These proteins help control immune responses and can keep T cells from killing cancer cells. When these proteins are blocked, breakdowns in the immune system are released and T cells are better able to kill cancer cells. Immune therapy is a technique that uses immune checkpoint inhibitors to treat a specific type of cancer, a recent discovery.
That's a drug that blocks proteins. Examples of immune checkpoint inhibitors include pembrolizumab (Keytruda), ipilimumab (Yervoy), nivolumab (Opdivo) and atezolizumab (Tecentriq).