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Topic starter 23/05/2022 12:38 pm
The HLA system (human leucocyte antigens - tissue compatibility antigens) regulates the immune response by controlling such important physiological processes as the interaction of immunocompetent cells of the body, cell recognition, and the launch and implementation of the immune response. Do you know the diseases in which it is recommended to carry out HLA typing? And is the importance of HLA typing so great?
23/05/2022 12:40 pm
The HLA system can help solve such important medical problems as organ and tissue transplantation, the fight against cancer and autoimmune diseases, etc. The HLA genotype is necessarily taken into account when selecting a donor for the transplantation procedure. The favorable prognosis of organ transplantation is higher with the maximum similarity of the donor and recipient in terms of tissue compatibility antigens. The relationship between HLA-antigens and the propensity to a number of diseases has also been proven. It is recommended to carry out mandatory HLA typing for all adult patients when they are diagnosed with acute myeloid leukemia, acute lymphoblastic leukemia, etc.
23/05/2022 1:00 pm
Some types of leukemia, as I remember
Topic starter 25/05/2022 7:36 am
@morphism @ekaterina-gribacheva Are there other systems for regulating immunity?
25/05/2022 7:39 am
@benzol00 for example - Nanotechnology. In this case nanomaterials can affect the immunity in a desired way for an organism.
Topic starter 28/05/2022 2:06 pm
@morphism And here in more detail , do you have links to research ?
03/06/2022 12:18 pm
@morphism And here in more detail , do you have links to research ?
https://www.mdpi.com/journal/ijms/special_issues/nanomaterials_Immune