Immunology Paul Ehrlich
On March 14 was born Paul Ehrlich - one of the founders of immunology. In this thread, I propose to recall his main scientific achievements
I start then! His foremost achievements were finding a cure for syphilis in 1909. His laboratory discovered arsphenamine (Salvarsan), the first effective medicinal treatment for syphilis, thereby initiating and also naming the concept of chemotherapy.
Mast cells were first described by Paul Ehrlich in 1878 in his doctoral dissertation, where he also characterized their granules. Ehrlich mistakenly decided that mast cells nourish the surrounding tissues, so he called them Mastzellen (from him. Mast — fatten). Subsequently, it was shown that mast cells are functionally related to the immune system)
In 1885, Paul Ehrlich received the first evidence of the existence of a blood-brain barrier. He found that the dye injected into the rat's bloodstream had spread to all organs and tissues except the brain
I recalled the scientific discussions of Erlich and Mechnikov in favor of humoral or cellular immunity
@morphism as far as I know, salvarsan also had the name "drug 606", and in the laboratory of Paul Ehrlich 605 other organic arsenic compounds were tested before the discovery of Salvarsan, which turned out to be ineffective. It sounds incredible
If we talk about immunology, it was Paul Ehrlich who first used the term "antibody" and proposed the theory of humoral immunity
why did you decide to dedicate the topic separately to Erlich?
@argentum I think, he is a very outstanding scientist who laid the foundations of immunology
@argentum On March 14 we talked about Paul Ehrlich at the university, because the date of his birth is March 14. That is why I decided to start this thread on this forum. I didn't say he was more or less outstanding compared to other scientists