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Drug discovery What the difference between LogP and LogD in Drug Design?

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morphism
 morphism
(@morphism)
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Topic starter 01/05/2022 7:16 am  

Hello, everyone! Often I see that scientist prefer to use LogD as a property to predict in comparison to LogP - why is it so? Could you explain?


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Antony10
 Antony10
(@antony10)
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06/05/2022 4:48 pm  

I was looking for information about this, but I didn't find anything. Now I'm very interested myself)


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morphism
 morphism
(@morphism)
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Posts: 555
Topic starter 07/05/2022 8:11 am  

@antony10 😀 Cannot agreed more. It looks like that there are some misconceptions about these terms.


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Antony10
 Antony10
(@antony10)
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10/05/2022 11:53 am  

@morphism I hope someone will be able to help us figure this out 🙄 


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morphism
 morphism
(@morphism)
Honorable Member
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Posts: 555
Topic starter 12/05/2022 9:21 am  

@antony10 yep, could it be connected to pH value?


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