Genetics Genetic baggage: what is it?
Hello, everyone! Do you know what is "genetic baggage"?
The genetic load is the accumulation of lethal and sublethal negative mutations, which cause a pronounced decrease in the viability of individuals, or their death, when they pass into the homozygous state.
You probably meant the concept of "genetic load"?
If you were referring to the genetic load, then this is the difference between the fitness of the average genotype in the population and the fitness of some reference genotype, which may be either the best present in the population or the theoretically optimal genotype. An average individual taken from a population with a low genetic load, usually when grown under the same conditions, will have more surviving offspring than an average individual from a population with a high genetic load. Genetic load can also be considered as a decrease in fitness at the population level compared to what would be in the population if all people had a reference genotype of high fitness. A high genetic load can put the population at risk of extinction .
"genetic baggage" can also describe the transposons hiding in our genomes, the historical record of our genomes that survived traumatic invasions during evolution. Transposons are repetitive DNA sequences that are able to move (transpose) from one place to another in the genome (a complete set of genetic instructions of the organism) and are considered important invaders of our genomes during evolution.
It's so many different values)
@ekaterina-gribacheva Is it also something we could use as trace for better understanding of evolution?